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DXA scans followed 155 participants at baseline, with 103 completing both baseline and week 36 scans, to monitor changes in muscle and fat

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GLP-1s Direct Biological Impact in the Brain Beyond their systemic metabolic effects, GLP-1 medications exert direct biological actions in the brain through widespread expression of incretin (GLP-1) receptors in regions critical for cognition, including the hippocampus, prefrontal cortex, and hypothalamus [14]

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Compounded versions require patients to draw precise amounts from vials, which has led to reported administration errors where patients accidentally injected doses up to 10 times higher than prescribed, causing severe nausea, vomiting, abdominal pain, and weakness