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Aldehydes induce localized micronutrient deficiencies initiating a cascade of metabolic disturbances in hundreds of metabolic pathways, cause oxidative stress, inactivate proteins by adduct formation, and bind to DNA, ultimately causing mutations and strand breakage
The paper assessed efficacy endpoints and safety observations within that controlled setting
The PA form asks for three to six months of documented lifestyle intervention with weight or A1c data
Other big questions remain, like whether the drug could also help people with other types of liver disease
References Neelakantan, H., Vance, V., et al
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