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A major concern in the treatment of patients with T2DM is to identify a therapeutic agent that can prevent the gradual declines in -cell function and mass

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It stimulates the brain and may work by increasing the amount of dopamine (a neurotransmitter used by neurons for communication) in the brain by reducing the reuptake of dopamine into neurons

Briefly, 4-m sections of formalin-fixed and paraffin-embedded tissues were deparaffinized using Bond Dewax Solution (Leica Biosystems Newcastle Ltd.) and antigen retrieval was achieved by incubation with Bond Epitope Retrieval Solution 1 (Leica Biosystems Newcastle Ltd.) for 20 minutes at 98