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The reported outcome of this campaign was a candidate that retained agonist activity at amylin/calcitonin-family receptors while displaying a markedly extended pharmacokinetic profile in the authors' preclinical models, and reduced food intake in rodent models following administration

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These receptors activate the transcription of the human insulin receptor gene, thereby stimulating the expression of insulin receptors improving insulin-mediated glucose transport 14

Experimental Protective Role : May protect the digestive system from injury caused by medications (NSAIDs) or environmental toxins