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Sermorelin is a single peptide acting on a single receptor (GHRH) with a 10 to 12 minute half-life

People with a family history of medullary thyroid or patients with multiple endocrine neoplasia syndrome type 2, and people with known serious hypersensitivity, should avoid usage

It's not currently known why this is

The mechanisms underlying this observed survival benefit could include the correction of abnormal cellular nucleotide, protein, and lipid synthesis