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Moreover, disproportionality analyses are intended to detect statistical associations rather than establish causality

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Furthermore, melatonin can be transferred by hydrogen atoms (hydrogen atom transfer, HAT), proton-coupled electron transfer (proton-coupled electron transfer, PCET), free radical addition, substances (radical adduct formation, RAF), single-electron transfer (SET), sequential electron-proton transfer (SEPT), and other mechanisms that directly remove peroxy groups (peroxyl radical, ROO), hydroxyl radical (OH), OO groups (nitric oxide, NO), and other free radicals (58)

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