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Response: We appreciate MedPAC's concerns, but as MedPAC acknowledges in its comment, the Congress would need to change current law to implement MedPAC's suggestions

Failure to fully rehabilitate traumatic injuries dramatically amplifies knee OA risk

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Furthermore, each batch undergoes testing for endotoxins using the Limulus Amebocyte Lysate (LAL) assay to ensure it is free from bacterial contaminants that could interfere with experimental results, particularly in cell-based or in vivo studies