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Although current evidence supports broad applicability across BMI, diabetes status, and fibrosis stages F2-F3, subgroup analyses suggest attenuated responses in non-obese patients and in certain ethnic groups (Hispanic patients in ESSENCE), emphasizing the need for precision medicine approaches incorporating anthropometric, genetic (e.g., PNPLA3, HSD17B13), and metabolic profiling

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Aqua Res 47:28352843 Adeshina I, Paray B, Bhat E, Sherzada S, Fawole O, Bawa D, da Cruz T, Tiamiyu L (2024) Effects of dietary -mannanase on the growth, antioxidant, and immunes responses of African catfish, Clarias gariepinus , and its challenge against Aeromonas hydrophila infection