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2 Patient results pretreatment showed an elevated fibrinogen, CD62p, PAC-1, and platelet aggregation rates when compared to the controls, while NO was lower in this cohort when compared to controls

SP might inactivate KEAP1, which allowed NRF2 to escape ubiquitination, accumulate within the cell, and translocate to the nucleus 28

For references and more information , see the section on copper in the in-depth article on Immunity