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Science 317 , 369372 (2007)

Dysaesthesia was also reported at higher rates with the Wegovy 7.2mg injection (22.9%) and appears to be a class-related phenomenon at higher GLP-1 agonist doses

Serious Health Complications Linked to GLP-1 Weight Loss Drugs Some GLP-1 patients in Dallas-Fort Worth have experienced severe side effects and health problems

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A 2025 study published in JAMA Network Open found that most patients with obesity discontinue GLP-1 therapy within a year, particularly those without type 2 diabetes 1