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Exendin-4 (an endogenous insulin releasing incretin, GLP-1) reduces A accumulation and tau hyperphosphorylation in cellular and animal models of AD (85, 151, 153156)

Insulin primarily enters the brain via selective, saturable transport across the blood-brain barrier (BBB) 373,374,375 Peripherally produced insulin can also be actively transported into the brain via an endocytic-exocytic mechanism

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Abstract Primary carnitine deficiency (PCD) not treated with L-Carnitine can lead to sudden cardiac death

First, because there were not many studies directly comparing TZD and GLP-1RA, liver biopsy-based outcomes and liver fat content confirmed via CAP were evaluated through indirect comparison