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Direct increases in collagen mRNA production occur across the effective concentration range of 0.01 to 100 nanomolar

In cultured human fibroblasts, micromolar concentrations of AEDG have been reported to induce telomerase activity in cells that would otherwise be telomerase-negative, with corresponding telomere lengthening over multiple passages (Khavinson et al., 2003)

in Nature (1980)