Measurement of L-CN and GBB The compounds were separated using triple quadrupole liquid chromatography mass spectrometer (LCMS, AB Sciex, QTRAPTM 4500, China), with the mass spectrometer set to positive electrospray ionization mode and predetermined multiple reaction monitoring (MRM) scans
The accelerating effect in migration is consistent with a previous study that was conducted in tendon fibroblasts
Additionally, treatment with 10 nM E2, for 7 days, stimulated differentiation to the neuronal lineage, and inhibited differentiation to astrocytes (Zhang et al., 2019)
It should be noted that this study was funded by Novo Nordisk, the pharmaceutical company that produces semaglutide
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