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When hemorrhagic shock occurs, the endothelial barrier is damaged, CS, HA, and HS in the glycocalyx are shed, and the permeability of pulmonary vessels is markedly elevated

Conflicts of interest The authors have no conflicts of interest to declare

doi: 10.1038/nature24661 118 LamasBRichardMLLeducqVPhamHPMichelMLDa CostaGet al

Alternatively, they might synergistically enhance angiogenesis through different mechanismsBPC-157 via VEGF upregulation and TB-500 through direct effects on endothelial cells