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This is consistent with central sensitization research more broadly, where initial sensitization episodes lower the threshold for future episodes

Pair rotation with good technique, basic site prep, and careful tracking

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Neurons responsiveness to hunger and satiety signals (as ghrelin, cholecystokinin, and PYY) are also modulated by body energy stores (represented by leptin and insulin).3 The aim of this article is to review the role of gut hormones as mediators of feeding behavior and of the different nutrients in modulating gut hormones production