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Aspartic acid (Asp) residues are particularly prone to hydrolysis-related degradation

Further, while personal anecdotes offer a snapshot of an individual's experience, they arent good indicators of potential long-term effects, rare side effects, or whether similar results would occur in a broader population

These multimers promote vascular intima injury, which increases endothelial permeability, monocyte adhesion, and macrophage accumulation, leading to plaque development ( The polyol pathway consumes up to 30% of intracellular glucose under hyperglycemic conditions, with aldose reductase converting glucose to sorbitol in an NADPH-dependent reaction that depletes this critical cofactor required for glutathione reductase activity (Gupta, 2024)

It means we do not yet know whether it does