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A phase 2 randomised controlled trial published in the New England Journal of Medicine (2023) reported substantial weight loss and improvements in glycaemic parameters, though the trial was conducted in a closely monitored clinical setting with defined eligibility criteria

The results showed a 20% reduction in major adverse cardiovascular events (MACE), defined as cardiovascular death, non-fatal heart attack, or non-fatal stroke

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ZLI-9017) were used, according to the manufacturers instructions

For example, the Inuit would consume, on average, 120mg of calcium per day, compared to the recommended daily intake of 800mg