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Genne P, Dimanche-Boitrel MT, Mauvernay RY, et al

FIGURE 2 In addition to be influenced by total intake of TMA precursors, TMAO levels can also be reduced by some bioactive compounds in nutrients

The STAT News coverage noted that if the FDA ultimately reclassifies the compounds and they are produced by compounding pharmacies, clinicians would have discretion to prescribe them outside the narrow indications under review, meaning a substance reviewed only for ulcerative colitis could legally be prescribed for any purpose a physician deemed appropriate

These findings further extend the utility of GSTO1 inhibitors as anti-inflammatory agents

doi: 10.1158/1940-6207.CAPR-12-0275 338 LevingstonCAYoungMRI