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Continuous use without breaks can reduce receptor sensitivity and potentially cause copper dysregulation

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[DOI] [PubMed] [Google Scholar] 196.Duda-Chodak A., Tarko T., Satora P., Sroka P

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Due to this, the researchers performing this study proposed that atrophied sebaceous glands and their decreased production of sebum are likely a key tipping point resulting in impaired corneocyte shedding in the follicle