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In addition to the local control of blood flow, the autonomic nervous system mediates global control of blood flow including changes in cardiac output and control of arterial BP: while the sympathetic nervous system (SNS) controls arterial hypertension, the parasympathetic nervous system contributes primarily to the regulation of cardiac function

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4.4.3 Therapeutic implications in non-cirrhotic MASLD/MASH In non-cirrhotic MASLD/MASH with elevated fasting circulating BCAAs, dietary BCAA restriction or avoidance of supplementation may improve metabolic outcomes

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CD44 Two human genetic studies have suggested that polymorphisms in the CD44 gene may account for variations in toxicity following paracetamol overdose [39, 42]

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