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Coma from low serum sodium occurred in 5 of these patients.[6] Coffee enemas cause electrolyte imbalance, which has resulted in serious infections, dehydration, colitis, constipation, and death.[7] References: REFERENCES 1

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Importantly, many peptide programs historically failed not because they were scientifically unsound, but because they were misaligned with regulatory frameworks, economic realities, or the prevailing standards of evidence at the time of evaluation

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