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TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum

Animal experimental evidence Osteoclast precursor (RAW264.7) experiment: AOD 9604 significantly inhibited RANKL induced osteoclast formation, reduced the number of TRAP positive multinucleated cells, and decreased bone resorption pit formation

PMC 2928224