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This difference may be due to the estimand choice of Pan et al., which is not reported, and the influence of additional studies that did not match our target population as Pan et al.s NMA had much broader eligibility criteria, with some studies including participants with T2D or using intensive behavioural therapy

Had a patient who kept eating her normal portions and wondered why she felt terrible

People with PCOS have higher levels of leptin, which may at first sound like they have better appetite regulation

This observation is consistent with previous reports revealing that GLP-1R signaling exerts a negative modulatory effect on T-cell function and antagonism of this receptor can potentiate antitumor immune responses (38,39)

Can people with lean PCOS use GLP 1s