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doi: 10.1017/S0317167100015109 76

Ultrasound-guided perineural vitamin B12 has the advantage of precise delivery of high-dose vitamin B12 directly around the nerve (the results need to be viewed in the context that this was only a case study)

It has been extensively studied in research settings for its potential role in tissue repair, wound healing, and gastrointestinal protection

In some embodiments, local otic delivery of the auris formulations or compositions described herein allows for controlled release of active agents to auris structures and overcomes the drawbacks associated with systemic administration (e.g., low bioavailability of the drug in the endolymph or perilymph, variability in concentration of the drug in the external, middle and/or internal ear)

3.Insert the needle into the GHK-Cu vial at an angle