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BDNF knockdown experiments further cement its role: mice with conditional BDNF deletion in the ventral tegmental area (VTA) or hippocampus develop spontaneous depressive phenotypes, even in the absence of ethanol, while BDNF infusion into these regions rescues ethanol-induced anhedonia (Zhong et al

Measurement of glutathione Total glutathione (GSH) was measured spectrophotometrically in the BALF, plasma, and tissues as previously described [17]

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Slower stomach emptying Food leaves the stomach more gradually, stretching out the feeling of fullness and smoothing post-meal blood-sugar peaks