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in catabolic research models suggest that IGF-1 LR3 may be more anabolic than IGF-1 because it appears to bind poorly to IGF-binding proteins

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Important: All cited research reflects preclinical findings from animal and cell studies

He also adds that rapid weight loss itself can cause issues

13 Twincretins: Dual GLP-1 and GIP Receptor Agonists Research on incretin-based therapies for T2DM has seen an exponential increase in the past three decades