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Cysteine is pluripotent : rate-limiting component in GSH synthesis, source of taurine and inorganic sulphate that facilitate the removal of RXS (Figure 2) , key to proper protein folding in the ER (143), and seemingly even more important than GSH for redox control (105)

Control group An age-appropriate group of neurotypical children meeting the predefined eligibility criteria was recruited as healthy controls and included in the metabolomic analyses

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Urine was vortexed and then diluted five times with phosphate-buffered saline before proceeding to the next step