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Efficacy: What the Head-to-Head Trial Showed In the head-to-head 72-week SURMOUNT-5 trial of 751 adults with obesity without diabetes, tirzepatide reduced body weight by an average of about 20.2% versus 13.7% for semaglutide

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Zihui Wang for providing valuable feedback on the manuscript revision

When to Seek Medical Attention According to prescribing information, patients should contact their healthcare provider immediately if experiencing: Severe abdominal pain that does not go away Signs of allergic reaction (swelling of face, lips, tongue, or throat

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