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Studies have demonstrated that loss of mTOR activity may be detrimental during PD, as mTOR dysfunction has been shown in animal models of PD to lead to the death/apoptosis of dopaminergic neurons 11,12

Microglia, discovered by Pio del Rio-Hortega [439441], are the resident immune cells of the CNS and play a critical role in neuroinflammation, host defense against pathogens, and injury response [442]

It appears in sexual-function pharmacology because melanocortin agonists have been studied for erectile and sexual-motivation effects

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NagashimaMWatanabeTTerasakiMTomoyasuMNohtomiKKim-KaneyamaJet alNative incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice