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In individuals without established CVD but with multiple cardiovascular risk factors (such as age 55 years, obesity, hypertension, smoking, dyslipidaemia or albuminuria), a GLP-1 RA with proven benefit could be used to reduce MACE, or an SGLT2i with proven benefit could be used to reduce MACE and HF and improve kidney outcomes

Its important to note that the study just found a link between being on a GLP-1 medication and having trouble with taste or smellit did not say that GLP-1s cause these issues

L.KaganJ.PanjabiS

These typically subside during the first 48 weeks

In addition, inter-population variation in genetic background, particularly in oxidative stressresponse genes and xenobiotic-metabolizing enzymes, may modify individual susceptibility to pollution-related reproductive toxicity