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Underdosing or Missed Injections If your dose hasnt been adjusted in monthsor if injections are inconsistentthe medication may no longer be at an optimal therapeutic level

Whilst metreleptin monotherapy supports weight loss in obese individuals, it is not clinically meaningful with a mean 1.5 kg additional weight loss over 24 weeks noted in a previous trial [87]

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Association between hypothyroidism and hepatocellular carcinoma: a case-control study in the United States