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However, these studies did not have data on long-term risk and eight did mention people developing new lesions following use

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Renal function is an important consideration, as NSAIDs can impair kidney function, especially in individuals with existing renal impairment, dehydration (which may occur with Wegovy-related vomiting or diarrhoea), or those taking other nephrotoxic medications

Estradiol stimulates proliferation of neural progenitor cells in a time- and dose-dependent manner (201, 206)