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Originally isolated from human plasma by Loren Pickart in 1973, this copper peptide exhibits a concentration-dependent decline with age, decreasing from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60

A novel prodrug-based strategy to increase effects of bumetanide in epilepsy

This approach will tend to result in weight-adjusted doses that are larger for women compared with men and smaller for older and obese patients

Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults

These points underscore the importance of maintaining adequate cobalamin levels