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Bacterial infections are among the most life-threatening healthcare challenges, accounting for approximately 13.6% of global mortality and affecting 1 in 8 individuals worldwide (Appanna, 2018)

Bailey CJ, et al

10.1136/gut.2009.184176 29 LiY

Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metab 24(6):795806

For example, they reported that beta-lactam resistance genes such as bla OXA-1 and bla TEM-1 were not detected before antibiotic treatment, but increased during antibiotic treatment and subsequently were not detected after antibiotic treatment 6