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Seizure types in COQ2 deficiency include focal seizures with altered consciousness, persistent partial seizures, myoclonic seizures, and status epilepticus (122, 134, 135)

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This finding indicates that epigenetic variation, which may well be susceptible to contextual and other environmental influences, has a greater effect on serum UA than the identified genetic factors and certainly deserves further investigation in PD

The peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool