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Current findings revealed that levels of TNF- and IL6 were substantially increased in CCI rats and attenuated by nicorandil treatment

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(2) The Bile Acid Signaling and Tryptophan-Indole Metabolism Module (high-priority candidates, yet lacking closed-loop anchors)

The sum of the data in relation to riluzole suggests that riluzoles main mechanism may not wholly depend on PKC downregulation, a known property of the drug, yet PKC downregulation may provide added benefit to other riluzole effects for an overall ultimate neuroprotective effect

[DOI] [PubMed] [Google Scholar] 2.Hopkins F.G