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In mechanistic terms, 5-Amino-1MQ is studied as a means of conserving cellular SAM and NAD that would otherwise be consumed by NNMT activity a pathway of interest in energy-metabolism and adipose-tissue research

Chem Biol Inter 129:6176 Van den Berg M, Sanderson T, Kurihara N, Katayama A (2003) Role of metabolism in the endocrine-disrupting effects of chemicals in aquatic and terrestrial systems

Oral dosing appears to work in rodent GI-injury models

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