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It works by targeting three hormone receptors involved in regulating appetite, blood sugar and energy balance: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide) and glucagon

Whereas the conventional imaging methods such as ultrasonography, computed tomography (CT), and magnetic resonance imaging have proven to display low sensitivity, selective arterial calcium stimulation test and endoscopic ultrasound are invasive and operator-dependent 6,7

10.1046/j.1471-4159.2003.01854.x J

Researchers designing combination protocols typically run controls with each compound in isolation alongside the combination arms to distinguish additive from synergistic effects and to identify which compound is driving each observed outcome

The medication still suppresses appetite and slows gastric emptying