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Some of the most common complaints include: Headache Swelling Rash Facial flushing Itchy skin Dizziness Numbness Diarrhea Vomiting High blood pressure Cold symptoms Anxiety Causes of Vitamin B12 Overdose Vitamin B12 is a water-soluble vitamin, which means that when we ingest too much of it, the excess amounts are flushed out of the body through urine

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(1) Studies on the Validation of In Vivo Obesity Intervention Effects A large number of in vivo animal experiments have confirmed that it exerts significant weightloss and fatreducing effects with favorable safety profiles.In a mouse model of highfat dietinduced obesity, administration of 20 mg/kg NNMTi daily for 11 days resulted in a significant reduction in body weight

This, of course, doesnt necessarily mean that the low B12 is whats causing the weight gain

Confirm low cobalamin (and folate/MMA) before and during therapy