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10.1016/bs.apcsb.2023.02.014 Adv

A research piece in JAMA from January 2025, examining over 125,000 individuals who were overweight or obese, indicated that almost 47% of participants with type 2 diabetes and 65% without diabetes ceased using their prescribed GLP-1s within twelve months of initiation

When were insulin resistant, our subcutaneous fat (the fat beneath the skin) doesnt respond as well to insulin as it should, and insulin struggles to move fat into these cells to be stored

However, they may occur at any age and affect approximately 3% of the population, with the lip being the most common location followed by the gingiva