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Secondary outcomes showed semaglutide reduced myocardial infarction (HR 0.81) and stroke (HR 0.84) versus sitagliptin, while tirzepatide was non-inferior to dulaglutide for mortality, myocardial infarction, and stroke

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Possible side effects include mild digestive symptoms like bloating or nausea

Other side effects such as headaches, dizziness, joint pain, and fatigue were equally common in both the liraglutide and placebo groups, occurring in 5-15% of cases