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CD8 + T cells treated with ML226 appeared to be able to rewire 2-OG metabolism, without major effects on 2-OGDD activity

Isaacs: For type 1 diabetes, we have good quality data showing that there's benefit to utilizing CGM in pregnancy in terms of improved glycemic outcomes as well as maternal and fetal outcomes compared with blood glucose monitoring

This translated to an absolute average weight reduction of approximately 52 pounds per participant

Reducing the risk of cardiovascular events such as stroke, non-fatal myocardial infarction, or stroke in patients with or without type 2 diabetes mellitus

By targeting appetite, blood sugar, and metabolism, they offer an alternative weight loss solution that supports steady progress, especially when paired with lifestyle changes and clinical oversight