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Hansen, Morten, Kristine Hare, Jens Holst, and Filip Knop
PubMed Randomized trialSemaglutide evidence2021 Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance Used for maintenance, discontinuation, and weight-regain discussions after semaglutide response
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Tirzepatide exerts its therapeutic effects through dual agonism of two key incretin receptors: the GIPR and the GLP-1R
These effects were generally mild to moderate in intensity and were most frequent during the dose escalation period, becoming less common as participants remained on their maintenance dose
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