Peissig PL, Costa VS, Caldwell MD, Rottscheit C, Berg RL, Mendonca EA, Page D
Peer-reviewed research has investigated AOD-9604 across animal models, ex vivo adipose tissue assays, and human clinical trials , with published studies appearing in journals including Endocrinology , the American Journal of Physiology Endocrinology and Metabolism , and Hormone Research
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doi:10.1201/9781315119540
First, a bacterial reverse mutation test (Ames test) assessed AOD9604s mutagenic potential using four histidine-dependent auxotrophic mutants of Salmonella typhimurium (TA1535, TA1537, TA98, TA100) and one tryptophan-dependent auxotrophic mutant of Escherichia coli (WP2 uvrA), using both plate incorporation and pre-incubation methods at doses of 0, 1.6, 8, 40, 200, 1,000, and 2,000 g AOD9604/plate