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This tonicity is both its strength and its limitation: it dramatically simplifies the protocol (2 injections per week), but abolishes pulsatility

The article adds that age, metabolic status and baseline metabolic syndrome severity also modulate side effect risk over months and years

Recently, antioxidants such as N-acetylcysteine (NAC), Myo-inositol, and micronutrients have been used in addition to the above medications to improve the chances of getting pregnant [4]

However, questions about the safety and effectiveness of such supplements remain.