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In clinical trials with high-dose semaglutide, nausea and vomiting were the most common side effects, which were associated with delayed gastric emptying and occurred in approximately 40% of participants in the studies

Regarding CSSS, there was a significant decrease in CSSS in all studied patients after intervention (the range decreased from an initial of 19118 to 1099 after intervention with a P-value of 0.025)

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