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In trials, Foundayo led to a 12% reduction in body weight and oral Wegovy led to about a 14% reduction
So so we are at maximum capacity is what you're saying
14,15 In the clinical experience of some authors of this Advisory, another approach is to maintain individuals at the lowest effective dose and escalate only as needed (i.e., when weight reduction ceases or efficacy wanes), although shortages or lack of insurance coverage of medications at lower doses may be a barrier
The OffRamp Strategy: Microdosing to Maintain Weight Loss Many physicians use a microdosing protocol as an offramp. Instead of quitting the medication cold turkey which almost always results in a massive surge of returning hunger and rebound weight gainpatients slowly taper down to a microdose, allowing their natural metabolism and gut microbiome to adapt over several months
