OPs interfere irreversibly with acetylcholinesterase (AChE) activity by phosphorylating its serine residues, resulting in hyper-excitation and disruption of neurotransmission in the central and peripheral nervous systems [37, 47]
Meanwhile, in the progression of gouty arthritis, single-cell transcriptomics can characterize the transcriptional profiles and functional differences between M1 and M2 macrophage subpopulations (116) scRNA-seq reveals that core transcription factors such as NF-B1 and STAT6, as well as non-coding RNAs including miR-155 and the lncRNA MALAT1, regulate the polarization process
Correlations between clinical patterns and causes of erythema multiforme majus, Stevens-Johnson syndrome, and toxic epidermal necrolysis: results of an international prospective study
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