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Possible side effects include: TRT Side Effects Elevated hematocrit (polycythemia) Acne or oily skin Fluid retention Testicular atrophy (manageable with hCG) Mood fluctuations during dose adjustments Potential fertility suppression Peptide Side Effects Injection site irritation or redness Temporary fluid retention Headaches or flushing Joint tightness (with GH-releasing peptides) Nausea (rare, more common with BPC-157) Sleep pattern adjustments Most side effects are dose-dependent and resolve with protocol adjustments

One of the most frustrating experiences for clinicians is the knowledge that treatments may work with time, but that patients often lack the psychological and financial resilience to withstand multiple cycles of stimulation and embryo transfers

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Some researchers suggest that immune-modulating peptides like thymosin alpha-1 are best started during remission, when the immune system is more stable and regulatory mechanisms have a better chance of re-establishing control