Victoza for diabetes (up to 1.8 mg), Saxenda for weight management (up to 3 mg) Oral GLP-1 option : Semaglutide (Rybelsus) is the only oral GLP-1 receptor agonist, taken once daily on an empty stomach with specific administration requirements: take with no more than 4 ounces of plain water, at least 30 minutes before eating, drinking, or taking other oral medications, and swallow tablets whole without breaking or chewing
doi: 10.2174/1570161115666170621080228 4 PolyzosSAKangESTsochatzisEAKechagiasSEkstedtMXanthakosSet al
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Benefits were more pronounced in younger adults (under 65), women, and patients with obesity, though confidence intervals often overlapped between subgroups